The effect of MinC on FtsZ polymerization is pH dependent and can be counteracted by ZapA.
نویسنده
چکیده
The min system prevents polar cell division in bacteria. Here, the biochemical characterization of the interaction of MinC and FtsZ from a Gram-positive bacterium, Bacillus subtilis, is reported. B. subtilis MinC inhibits FtsZ polymerization in a pH-dependent manner by preventing the formation of lateral associations between filaments. The inhibitory effect of MinC on FtsZ polymerization is counteracted by the presence of ZapA, a protein that promotes FtsZ filament bundling.
منابع مشابه
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عنوان ژورنال:
- FEBS letters
دوره 582 17 شماره
صفحات -
تاریخ انتشار 2008